SCOPe 2.05: Domain d3sdga1: 3sdg A:26-92

Lineage for d3sdga1 (3sdg A:26-92)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.1: Homeodomain-like [46689] (20 families)
   consists only of helices

5. Family a.4.1.0: automated matches [191447] (1 protein)
   not a true family

6. Protein automated matches [190674] (16 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:1773] [232223] (12 PDB entries)

8. Domain d3sdga1: 3sdg A:26-92 [249369]
   Other proteins in same PDB: d3sdga2
   automated match to d3sfia1
   protein/DNA complex; complexed with 3se

Details for d3sdga1

PDB Entry: 3sdg, 1.87 Å

PDB Description: ethionamide boosters part 2: combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole ethr inhibitors.

PDB Compounds: (A:) HTH-type transcriptional regulator EthR

SCOPe Domain Sequences for d3sdga1:

Sequence; same for both SEQRES and ATOM records:

>d3sdga1 a.4.1.0 (A:26-92) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
elailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvnqadm
alqtlae

Timeline for d3sdga1:

• d3sdga1 first appeared in SCOPe 2.04
  
• d3sdga1 appears in SCOPe 2.06
  
• d3sdga1 appears in the current release, SCOPe 2.08