SCOPe 2.06: Domain d3n3ia2: 3n3i A:1001-1099

Lineage for d3n3ia2 (3n3i A:1001-1099)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (476 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d3n3ia2: 3n3i A:1001-1099 [247852]
   automated match to d3mima_
   complexed with roc

Details for d3n3ia2

PDB Entry: 3n3i, 2.5 Å

PDB Description: crystal structure of g48v/c95f tethered hiv-1 protease/saquinavir complex

PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d3n3ia2:

Sequence; same for both SEQRES and ATOM records:

>d3n3ia2 b.50.1.1 (A:1001-1099) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmivgiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigftlnf

Timeline for d3n3ia2:

• d3n3ia2 first appeared in SCOPe 2.04
  
• d3n3ia2 appears in SCOPe 2.05
  
• d3n3ia2 appears in SCOPe 2.07
  
• d3n3ia2 appears in the current release, SCOPe 2.08