SCOPe 2.06: Domain d3dzqa_: 3dzq A:

Lineage for d3dzqa_ (3dzq A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d3dzqa_: 3dzq A: [245739]
   automated match to d3pp0b_
   complexed with ifc

Details for d3dzqa_

PDB Entry: 3dzq, 1.75 Å

PDB Description: human epha3 kinase domain in complex with inhibitor awl-ii-38.3

PDB Compounds: (A:) EPH receptor A3

SCOPe Domain Sequences for d3dzqa_:

Sequence, based on SEQRES records:

>d3dzqa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vhefakeldatnisidkvvgagefgevcsgrlklpskkeisvaiktlkvgytekqrrdfl
geasimgqfdhpniirlegvvtkskpvmivteymengsldsflrkhdaqftviqlvgmlr
giasgmkylsdmgyvhrdlaarnilinsnlvckvsdfglsrvleddpeaayttrggkipi
rwtspeaiayrkftsasdvwsygivlwevmsygerpywemsnqdvikavdegyrlpppmd
cpaalyqlmldcwqkdrnnrpkfeqivsildklirnpgslkiitsaaarpsnllld

Sequence, based on observed residues (ATOM records):

>d3dzqa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vhefakeldatnisidkvvgagefgevcsgrlklpskkeisvaiktlkvgytekqrrdfl
geasimgqfdhpniirlegvvtkskpvmivteymengsldsflrkhdaqftviqlvgmlr
giasgmkylsdmgyvhrdlaarnilinsnlvckvsdfglpirwtspeaiayrkftsasdv
wsygivlwevmsygerpywemsnqdvikavdegyrlpppmdcpaalyqlmldcwqkdrnn
rpkfeqivsildklirnplkiitnllld

Timeline for d3dzqa_:

• d3dzqa_ first appeared in SCOPe 2.04
  
• d3dzqa_ appears in SCOPe 2.05
  
• d3dzqa_ appears in SCOPe 2.07
  
• d3dzqa_ appears in the current release, SCOPe 2.08