Lineage for d3csfa2 (3csf A:357-522)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2045100Fold b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  4. 2045101Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families) (S)
    two constituent families are related by circular permutation
  5. 2045102Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)
  6. 2045125Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)
  7. 2045126Species Human (Homo sapiens) [TaxId:9606] [49572] (61 PDB entries)
  8. 2045169Domain d3csfa2: 3csf A:357-522 [245525]
    Other proteins in same PDB: d3csfa1, d3csfa3, d3csfa4
    automated match to d1e8wa2
    complexed with dw2

Details for d3csfa2

PDB Entry: 3csf (more details), 2.8 Å

PDB Description: crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor dw2
PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d3csfa2:

Sequence, based on SEQRES records: (download)

>d3csfa2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d3csfa2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3csfa2:

Click to download the PDB-style file with coordinates for d3csfa2.
(The format of our PDB-style files is described here.)

Timeline for d3csfa2: