SCOPe 2.08: Domain d4j51a_: 4j51 A:

Lineage for d4j51a_ (4j51 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d4j51a_: 4j51 A: [240281]
   automated match to d4j51b_
   complexed with n75

Details for d4j51a_

PDB Entry: 4j51, 2.3 Å

PDB Description: Cyrstal structure of protein tyrosine phosphatase Lyp catalytic domain complex with small molecular inhibitor L75N04

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 22

SCOPe Domain Sequences for d4j51a_:

Sequence, based on SEQRES records:

>d4j51a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mdqreilqkfldeaqskkitkeefaneflklkrqstkykadktypttvaekpknikknry
kdilpydysrvelslitsdedssyinanfikgvygpkayiatqgplsttlldfwrmiwey
svliivmacmeyemgkkkcerywaepgemqlefgpfsvsceaekrksdyiirtlkvkfns
etrtiyqfhyknwpdhdvpssidpileliwdvrcyqeddsvpicihcsagcgrtgvicai
dytwmllkdgiipenfsvfsliremrtqrpslvqtqeqyelvynavlelfkrqmdvirdk
hsg

Sequence, based on observed residues (ATOM records):

>d4j51a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mdqreilqkfldeaqskkitkeefaneflklkrqstkykadktypttvaekpknikknry
kdilpydysrvelslitdedssyinanfikgvygpkayiatqgplsttlldfwrmiweys
vliivmacmeyemgkkkcerywaepgemqlefgpfsvsceaekrksdyiirtlkvkfnse
trtiyqfhyknwpdhdvpssidpileliwdvrcyqeddsvpicihcsagcgrtgvicaid
ytwmllkdgiipenfsvfsliremrtqrpslvqtqeqyelvynavlelfkrqmdvirdkh
sg

Timeline for d4j51a_:

• d4j51a_ first appeared in SCOPe 2.04
  
• d4j51a_ appears in SCOPe 2.07