SCOPe 2.05: Domain d1tedb1: 1ted B:31-246

Lineage for d1tedb1 (1ted B:31-246)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (3 families)

5. Family c.95.1.2: Chalcone synthase-like [53914] (9 proteins)

6. Protein Polyketide synthase PKS18 [110758] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [110759] (2 PDB entries)
   Uniprot Q79FQ0

8. Domain d1tedb1: 1ted B:31-246 [238544]
   complexed with myr

Details for d1tedb1

PDB Entry: 1ted, 2.25 Å

PDB Description: Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis

PDB Compounds: (B:) pks18

SCOPe Domain Sequences for d1tedb1:

Sequence, based on SEQRES records:

>d1tedb1 c.95.1.2 (B:31-246) Polyketide synthase PKS18 {Mycobacterium tuberculosis [TaxId: 1773]}
tvavieglatgtprrvvnqsdaadrvaelfldpgqreriprvyqksrittrrmavdplda
kfdvfrrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapg
vdvaivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielcsvnav
faddindvvihslfgdgcaalvigasqvqeklepgk

Sequence, based on observed residues (ATOM records):

>d1tedb1 c.95.1.2 (B:31-246) Polyketide synthase PKS18 {Mycobacterium tuberculosis [TaxId: 1773]}
tvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmavdpldakfdv
frrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapgvdva
ivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielcsvnavfadd
indvvihslfgdgcaalvigasqvqeklepgk

Timeline for d1tedb1:

• d1tedb1 first appeared in SCOPe 2.04
  
• d1tedb1 appears in SCOPe 2.06
  
• d1tedb1 appears in the current release, SCOPe 2.08