SCOPe 2.03: Domain d4nuea_: 4nue A:

Lineage for d4nuea_ (4nue A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (145 PDB entries)

8. Domain d4nuea_: 4nue A: [238265]
   automated match to d3p5oa_
   complexed with edo, nue

Details for d4nuea_

PDB Entry: 4nue, 1.3 Å

PDB Description: Crystal structure of the first bromodomain of human BRD4 in complex with MS267 inhibitor

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4nuea_:

Sequence; same for both SEQRES and ATOM records:

>d4nuea_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelpte

Timeline for d4nuea_:

• d4nuea_ is new in SCOPe 2.03-stable
  
• d4nuea_ appears in SCOPe 2.04
  
• d4nuea_ appears in the current release, SCOPe 2.08, called d4nuea1