Lineage for d4nm0a1 (4nm0 A:26-383)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543788Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (2 species)
    CMGC group; GSK3 subfamily; serine/threonine kinase
  7. 2543789Species Human (Homo sapiens) [TaxId:9606] [69824] (51 PDB entries)
    Uniprot P49841 35-383 ! Uniprot P49841 35-384
  8. 2543821Domain d4nm0a1: 4nm0 A:26-383 [238059]
    Other proteins in same PDB: d4nm0a2
    automated match to d1j1bb_
    complexed with adp, cl, dtt, gol, mg

Details for d4nm0a1

PDB Entry: 4nm0 (more details), 2.5 Å

PDB Description: Crystal structure of peptide inhibitor-free GSK-3/Axin complex
PDB Compounds: (A:) Glycogen synthase kinase-3 beta

SCOPe Domain Sequences for d4nm0a1:

Sequence, based on SEQRES records: (download)

>d4nm0a1 d.144.1.7 (A:26-383) Glycogen synthase kinase-3 beta (Gsk3b) {Human (Homo sapiens) [TaxId: 9606]}
mkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaik
kvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarh
ysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsak
qlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdq
lveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytp
tarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

Sequence, based on observed residues (ATOM records): (download)

>d4nm0a1 d.144.1.7 (A:26-383) Glycogen synthase kinase-3 beta (Gsk3b) {Human (Homo sapiens) [TaxId: 9606]}
mkvsrdskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvl
qdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysr
akqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlv
rgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlve
iikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptar
ltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

SCOPe Domain Coordinates for d4nm0a1:

Click to download the PDB-style file with coordinates for d4nm0a1.
(The format of our PDB-style files is described here.)

Timeline for d4nm0a1: