Lineage for d4o75a1 (4o75 A:44-168)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1993780Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  4. 1993781Superfamily a.29.2: Bromodomain [47370] (2 families) (S)
  5. 1993941Family a.29.2.0: automated matches [191428] (1 protein)
    not a true family
  6. 1993942Protein automated matches [190615] (10 species)
    not a true protein
  7. 1993960Species Human (Homo sapiens) [TaxId:9606] [187641] (647 PDB entries)
  8. 1994049Domain d4o75a1: 4o75 A:44-168 [237373]
    Other proteins in same PDB: d4o75a2
    automated match to d3p5oa_
    complexed with 2rc, edo

Details for d4o75a1

PDB Entry: 4o75 (more details), 1.55 Å

PDB Description: crystal structure of the first bromodomain of human brd4 in complex with fostamatinib
PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4o75a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4o75a1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lptee

SCOPe Domain Coordinates for d4o75a1:

Click to download the PDB-style file with coordinates for d4o75a1.
(The format of our PDB-style files is described here.)

Timeline for d4o75a1:

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Domains from same chain:
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d4o75a2