SCOPe 2.05: Domain d4nnnx_: 4nnn X:

Lineage for d4nnnx_ (4nnn X:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

6. Protein Proteasome beta subunit (catalytic) [56252] (5 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (70 PDB entries)
   The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)

8. Domain d4nnnx_: 4nnn X: [236838]
   Other proteins in same PDB: d4nnnb_, d4nnnc_, d4nnnd_, d4nnne_, d4nnnf_, d4nnng_, d4nnnh_, d4nnnm_, d4nnnp_, d4nnnq_, d4nnnr_, d4nnns_, d4nnnt_, d4nnnu_, d4nnnv_
   automated match to d1rypk_
   complexed with ald, mg

Details for d4nnnx_

PDB Entry: 4nnn, 2.5 Å

PDB Description: yCP in complex with MG132

PDB Compounds: (X:) Proteasome subunit beta type-4

SCOPe Domain Sequences for d4nnnx_:

Sequence; same for both SEQRES and ATOM records:

>d4nnnx_ d.153.1.4 (X:) Proteasome beta subunit (catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddf

Timeline for d4nnnx_:

• d4nnnx_ first appeared in SCOPe 2.03
  
• d4nnnx_ appears in SCOPe 2.04
  
• d4nnnx_ appears in SCOPe 2.06
  
• d4nnnx_ appears in the current release, SCOPe 2.08