Lineage for d4nh9a_ (4nh9 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2537076Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 2537077Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 2537078Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)
  6. 2537079Protein HSP90 [55876] (3 species)
  7. 2537164Species Human (Homo sapiens) [TaxId:9606] [55878] (144 PDB entries)
    Uniprot P08238 10-220 # HSP 90-beta isoform ! Uniprot P07900 16-223
  8. 2537315Domain d4nh9a_: 4nh9 A: [236234]
    automated match to d1qy5a_
    complexed with 2lc

Details for d4nh9a_

PDB Entry: 4nh9 (more details), 2.77 Å

PDB Description: Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity
PDB Compounds: (A:) Endoplasmin

SCOPe Domain Sequences for d4nh9a_:

Sequence, based on SEQRES records: (download)

>d4nh9a_ d.122.1.1 (A:) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
sekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalsgneel
tvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstseli
gqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlk
eeasdyleldtiknlvkkysqfinfpiyvwssktetveepmeeeeaakeekeesddeaav
eeeeeekkpktkkvektvwdwelmn

Sequence, based on observed residues (ATOM records): (download)

>d4nh9a_ d.122.1.1 (A:) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
sekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalsgneel
tvkikcdkeknllhvtdtgvgmtreelvknflnkmteaqedgqstseligqfgvgfysaf
lvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeeasdyleldt
iknlvkkysqfinfpiyvwssktektvwdwelmn

SCOPe Domain Coordinates for d4nh9a_:

Click to download the PDB-style file with coordinates for d4nh9a_.
(The format of our PDB-style files is described here.)

Timeline for d4nh9a_: