SCOPe 2.03: Domain d4kbbb2: 4kbb B:1067-1291

Lineage for d4kbbb2 (4kbb B:1067-1291)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (3 proteins)
   overall fold is very similar to that of the STI family
   automatically mapped to Pfam PF07951

6. Protein Botulinum neurotoxin [50402] (2 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [50403] (3 PDB entries)

8. Domain d4kbbb2: 4kbb B:1067-1291 [235126]
   Other proteins in same PDB: d4kbba1, d4kbbb1
   automated match to d3btaa2
   complexed with cl, mg

Details for d4kbbb2

PDB Entry: 4kbb, 2.3 Å

PDB Description: structure of botulinum neurotoxin b binding domain in complex with both synaptotagmin ii and gd1a

PDB Compounds: (B:) botulinum neurotoxin type b

SCOPe Domain Sequences for d4kbbb2:

Sequence, based on SEQRES records:

>d4kbbb2 b.42.4.2 (B:1067-1291) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
sqsnieerykiqsyseylkdfwgnplmynkeyymfnagnknsyiklkkdspvgeiltrsk
ynqnskyinyrdlyigekfiirrksnsqsinddivrkedyiyldffnlnqewrvytykyf
kkeeeklflapisdsdefyntiqikeydeqptyscqllfkkdeestdeigligihrfyes
givfeeykdyfciskwylkevkrkpynlklgcnwqfipkdegwte

Sequence, based on observed residues (ATOM records):

>d4kbbb2 b.42.4.2 (B:1067-1291) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
sqsnieerykiqsyseylkdfwgnplmynkeyymfnagnknsyiklkkdspvgeiltrsk
ynqnskyinyrdlyigekfiirrkdivrkedyiyldffnlnqewrvytykyfkkeeeklf
lapisdsdefyntiqikeydeqptyscqllfkkdeestdeigligihrfyeseykdyfci
skwylkevkrkpynlklgcnwqfipkdegwte

Timeline for d4kbbb2:

• d4kbbb2 is new in SCOPe 2.03-stable
  
• d4kbbb2 appears in SCOPe 2.04
  
• d4kbbb2 appears in the current release, SCOPe 2.08