SCOPe 2.04: Domain d4k81d_: 4k81 D:

Lineage for d4k81d_ (4k81 D:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein cH-p21 Ras protein [52593] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52594] (104 PDB entries)
   Uniprot Q6P716

8. Domain d4k81d_: 4k81 D: [235113]
   automated match to d4k81f_
   complexed with gol, gtp, mg

Details for d4k81d_

PDB Entry: 4k81, 2.4 Å

PDB Description: Crystal structure of the Grb14 RA and PH domains in complex with GTP-loaded H-Ras

PDB Compounds: (D:) gtpase hras

SCOPe Domain Sequences for d4k81d_:

Sequence; same for both SEQRES and ATOM records:

>d4k81d_ c.37.1.8 (D:) cH-p21 Ras protein {Human (Homo sapiens) [TaxId: 9606]}
gamgsmteyklvvvgavgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldi
ldtagqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvg
nkcdlaartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

Timeline for d4k81d_:

• d4k81d_ first appeared in SCOPe 2.03
  
• d4k81d_ appears in SCOPe 2.05
  
• d4k81d_ appears in the current release, SCOPe 2.08, called d4k81d1