SCOPe 2.03: Domain d4ivda_: 4ivd A:

Lineage for d4ivda_ (4ivd A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d4ivda_: 4ivd A: [234911]
   automated match to d4ehza_
   complexed with 15t

Details for d4ivda_

PDB Entry: 4ivd, 1.93 Å

PDB Description: JAK1 kinase (JH1 domain) in complex with compound 34

PDB Compounds: (A:) Tyrosine-protein kinase JAK1

SCOPe Domain Sequences for d4ivda_:

Sequence, based on SEQRES records:

>d4ivda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
esggnhiadlkkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknk
nkinlkqqlkyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdk
eyytvkddrdspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmi
gpthgqmtvtrlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeal
lk

Sequence, based on observed residues (ATOM records):

>d4ivda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
hiadlkkeieilrnlyhenivkykgictgiklimeflpsgslkeylpknknkinlkqqlk
yavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrd
spvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvt
rlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

Timeline for d4ivda_:

• d4ivda_ is new in SCOPe 2.03-stable
  
• d4ivda_ appears in SCOPe 2.04
  
• d4ivda_ appears in the current release, SCOPe 2.08, called d4ivda1