Lineage for d4i5cb_ (4i5c B:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1436359Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 1436360Protein automated matches [190417] (18 species)
    not a true protein
  7. 1436481Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)
  8. 1436646Domain d4i5cb_: 4i5c B: [234809]
    automated match to d4ehza_
    complexed with c5i, edo

Details for d4i5cb_

PDB Entry: 4i5c (more details), 2.1 Å

PDB Description: The Jak1 kinase domain in complex with inhibitor
PDB Compounds: (B:) Tyrosine-protein kinase JAK1

SCOPe Domain Sequences for d4i5cb_:

Sequence, based on SEQRES records: (download)

>d4i5cb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
esggnhiadlkkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknk
nkinlkqqlkyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdk
eyytvkddrdspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmi
gpthgqmtvtrlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeal
lk

Sequence, based on observed residues (ATOM records): (download)

>d4i5cb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
hiadlkkeieilrnlyhenivkykgictegiklimeflpsgslkeylpknknkinlkqql
kyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddr
dspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtv
trlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

SCOPe Domain Coordinates for d4i5cb_:

Click to download the PDB-style file with coordinates for d4i5cb_.
(The format of our PDB-style files is described here.)

Timeline for d4i5cb_: