SCOPe 2.07: Domain d4hevb1: 4hev B:1-416

Lineage for d4hevb1 (4hev B:1-416)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (29 PDB entries)
   Uniprot P10845 1-419

8. Domain d4hevb1: 4hev B:1-416 [234647]
   Other proteins in same PDB: d4heva2, d4hevb2
   automated match to d4ej5a_
   complexed with axm, zn

Details for d4hevb1

PDB Entry: 4hev, 2.5 Å

PDB Description: Clostridium Botulinum Serotype A Light Chain Inhibited By Adamantane Hydroxamate

PDB Compounds: (B:) botulinum neurotoxin type a light chain

SCOPe Domain Sequences for d4hevb1:

Sequence, based on SEQRES records:

>d4hevb1 d.92.1.7 (B:1-416) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdtftnpeegdln
pppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwgg
stidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngy
gstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpn
rvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnka
ksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkv
lnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftkl

Sequence, based on observed residues (ATOM records):

>d4hevb1 d.92.1.7 (B:1-416) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipqmqpvkafkihnkiwviperdtftnpeegdlnppv
syydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvi
dtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngygstqyirfsp
dftfgfeesgagkfatdpavtlahelihaghrlygiainpnrvevsfeelrtfgghdakf
idslqenefrlyyynkfkdiastlnkaksivgttaslqymknvfkekyllsedtsgkfsv
dklkfdklykmlteiytednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlr
ntnlaanfngqnteinnmnftkl

Timeline for d4hevb1:

• d4hevb1 first appeared in SCOPe 2.03, called d4hevb_
  
• d4hevb1 appears in SCOPe 2.06
  
• d4hevb1 appears in the current release, SCOPe 2.08