SCOPe 2.04: Domain d4h25e2: 4h25 E:93-190

Lineage for d4h25e2 (4h25 E:93-190)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein automated matches [190374] (9 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187221] (385 PDB entries)

8. Domain d4h25e2: 4h25 E:93-190 [234613]
   Other proteins in same PDB: d4h25a1, d4h25a2, d4h25b1, d4h25d1, d4h25d2, d4h25e1
   automated match to d4h26e2
   complexed with ipa

Details for d4h25e2

PDB Entry: 4h25, 2.2 Å

PDB Description: tcr interaction with peptide mimics of nickel offers structure insights to nickel contact allergy

PDB Compounds: (E:) MHC class II antigen

SCOPe Domain Sequences for d4h25e2:

Sequence, based on SEQRES records:

>d4h25e2 b.1.1.2 (E:93-190) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rrvhpqvtvypaktqplqhhnllvcsvsgfypgsievrwfrngqeektgvvstglihngd
wtfqtlvmletvprsgevytcqvehpsvtspltvewra

Sequence, based on observed residues (ATOM records):

>d4h25e2 b.1.1.2 (E:93-190) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rrvhpqvtvypaktnllvcsvsgfypgsievrwfrngqeektgvvstglihngdwtfqtl
vmletvprsgevytcqvehpsvtspltvewra

Timeline for d4h25e2:

• d4h25e2 first appeared in SCOPe 2.03
  
• d4h25e2 appears in SCOPe 2.05
  
• d4h25e2 appears in the current release, SCOPe 2.08