SCOPe 2.05: Domain d3p6aa1: 3p6a A:411-623

Lineage for d3p6aa1 (3p6a A:411-623)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.87: DBL homology domain (DH-domain) [48064] (1 superfamily)
   multihelical; core: 5-helical bundle

4. Superfamily a.87.1: DBL homology domain (DH-domain) [48065] (2 families)
   automatically mapped to Pfam PF00621

5. Family a.87.1.0: automated matches [233075] (1 protein)
   not a true family

6. Protein automated matches [233076] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [233077] (2 PDB entries)

8. Domain d3p6aa1: 3p6a A:411-623 [233153]
   Other proteins in same PDB: d3p6aa2, d3p6ab2
   automated match to d1xcga1
   mutant

Details for d3p6aa1

PDB Entry: 3p6a, 2.5 Å

PDB Description: Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant)

PDB Compounds: (A:) Rho guanine nucleotide exchange factor 1

SCOPe Domain Sequences for d3p6aa1:

Sequence, based on SEQRES records:

>d3p6aa1 a.87.1.0 (A:411-623) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pksqvkrqevisellvteaahvrmlrvlhdlffqpmaeclffpleelqnifpsldeliev
hslfldrlmkrrqesgylieeigdvllarfdgaegswfqkissrfcsrqsfaleqlkakq
rkdprfcafvqeaesrprcrrlqlkdmiptemqrltkyplllqsigqnteepterekvel
aaeccreilhhvnqavrdmedllrlkdyqrrld

Sequence, based on observed residues (ATOM records):

>d3p6aa1 a.87.1.0 (A:411-623) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pksqvkrqevisellvteaahvrmlrvlhdlffqpmaeclffpleelqnifpsldeliev
hslfldrlmkrrqeslieeigdvllarfdgaegswfqkissrfcsrqsfaleqlkakqrk
dprfcafvqeaesrprcrrlqlkdmiptemqrltkyplllqsigqnteepterekvelaa
eccreilhhvnqavrdmedllrlkdyqrrld

Timeline for d3p6aa1:

• d3p6aa1 first appeared in SCOPe 2.03
  
• d3p6aa1 appears in SCOPe 2.04
  
• d3p6aa1 appears in SCOPe 2.06
  
• d3p6aa1 appears in the current release, SCOPe 2.08