SCOPe 2.08: Domain d3iw4a_: 3iw4 A:

Lineage for d3iw4a_ (3iw4 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3iw4a_: 3iw4 A: [232637]
   automated match to d3iw4c_
   complexed with lw4

Details for d3iw4a_

PDB Entry: 3iw4, 2.8 Å

PDB Description: crystal structure of pkc alpha in complex with nvp-aeb071

PDB Compounds: (A:) Protein kinase C alpha type

SCOPe Domain Sequences for d3iw4a_:

Sequence, based on SEQRES records:

>d3iw4a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ldrvkltdfnflmvlgkgsfgkvmladrkgteelyaikilkkdvviqdddvectmvekrv
lalldkppfltqlhscfqtvdrlyfvmeyvnggdlmyhiqqvgkfkepqavfyaaeisig
lfflhkrgiiyrdlkldnvmldseghikiadfgmckehmmdgvttrefcgtpdyiapeii
ayqpygksvdwwaygvllyemlagqppfdgededelfqsimehnvsypkslskeavsick
glmtkhpakrlgcgpegerdvrehaffrridweklenreiqppfkpkvcgkgaenfdkff
trgqpvltppdqlvianidqsdfegfsyvnpqfvhpilq

Sequence, based on observed residues (ATOM records):

>d3iw4a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ldrvkltdfnflmvlgkgsfgkvmladrkgteelyaikilkkdvviqdddvectmvekrv
lalldkppfltqlhscfqtvdrlyfvmeyvnggdlmyhiqqvgkfkepqavfyaaeisig
lfflhkrgiiyrdlkldnvmldseghikiadfgmckehmmdgvttrefcgtpdyiapeii
ayqpygksvdwwaygvllyemlagqppfdgededelfqsimehnvsypkslskeavsick
glmtkhpakrlgcgpegerdvrehaffrridweklenreiqppfkpkvfdkfftrgqpvl
tppdqlvianidqsdfegfsyvnpqfvhpilq

Timeline for d3iw4a_:

• d3iw4a_ first appeared in SCOPe 2.03
  
• d3iw4a_ appears in SCOPe 2.07