SCOPe 2.06: Domain d3h3bb2: 3h3b B:166-191

Lineage for d3h3bb2 (3h3b B:166-191)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.9: Growth factor receptor domain [57184] (2 families)

5. Family g.3.9.0: automated matches [232406] (1 protein)
   not a true family

6. Protein automated matches [232407] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [232408] (11 PDB entries)

8. Domain d3h3bb2: 3h3b B:166-191 [232410]
   Other proteins in same PDB: d3h3ba1, d3h3ba3, d3h3bb1, d3h3bb3, d3h3bc1, d3h3bc2, d3h3bd1, d3h3bd2
   automated match to d1n8zc3

Details for d3h3bb2

PDB Entry: 3h3b, 2.45 Å

PDB Description: Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain

PDB Compounds: (B:) Receptor tyrosine-protein kinase erbB-2

SCOPe Domain Sequences for d3h3bb2:

Sequence, based on SEQRES records:

>d3h3bb2 g.3.9.0 (B:166-191) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rsrachpcspmckgsrcwgessedcq

Sequence, based on observed residues (ATOM records):

>d3h3bb2 g.3.9.0 (B:166-191) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rsrachpcspmcrcwgessedcq

Timeline for d3h3bb2:

• d3h3bb2 first appeared in SCOPe 2.03
  
• d3h3bb2 appears in SCOPe 2.05
  
• d3h3bb2 appears in SCOPe 2.07
  
• d3h3bb2 appears in the current release, SCOPe 2.08