SCOPe 2.04: Domain d1zvda_: 1zvd A:

Lineage for d1zvda_ (1zvd A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (2 families)
   automatically mapped to Pfam PF00632

5. Family d.148.1.0: automated matches [227207] (1 protein)
   not a true family

6. Protein automated matches [226939] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225255] (8 PDB entries)

8. Domain d1zvda_: 1zvd A: [230463]
   automated match to d3tuga_
   complexed with na, po4

Details for d1zvda_

PDB Entry: 1zvd, 2.1 Å

PDB Description: Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain

PDB Compounds: (A:) Smad ubiquitination regulatory factor 2

SCOPe Domain Sequences for d1zvda_:

Sequence; same for both SEQRES and ATOM records:

>d1zvda_ d.148.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
krdlvqklkilrqelsqqqpqaghcrievsreeifeesyrqvmkmrpkdlwkrlmikfrg
eegldyggvarewlyllshemlnpyyglfqysrddiytlqinpdsavnpehlsyfhfvgr
imgmavfhghyidggftlpfykqllgksitlddmelvdpdlhnslvwilenditgvldht
fcvehnaygeiiqhelkpngksipvneenkkeyvrlyvnwrflrgieaqflalqkgfnev
ipqhllktfdekeleliicglgkidvndwkvntrlkhctpdsnivkwfwkaveffdeerr
arllqfvtgssrvplqgfkalqgaagprlftihqidactnnlpkahtcfnridippyesy
eklyeklltaiee

Timeline for d1zvda_:

• d1zvda_ first appeared in SCOPe 2.03
  
• d1zvda_ appears in SCOPe 2.05
  
• d1zvda_ appears in the current release, SCOPe 2.08