SCOPe 2.06: Domain d4ltwa_: 4ltw A:

Lineage for d4ltwa_ (4ltw A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Ancestral gene [230150] (1 PDB entry)

8. Domain d4ltwa_: 4ltw A: [230151]
   automated match to d3gn8a_
   complexed with 486, gol, so4, str

Details for d4ltwa_

PDB Entry: 4ltw, 2.04 Å

PDB Description: Ancestral Ketosteroid Receptor-Progesterone-Mifepristone Complex

PDB Compounds: (A:) Ancestral Steroid Receptor 2

SCOPe Domain Sequences for d4ltwa_:

Sequence; same for both SEQRES and ATOM records:

>d4ltwa_ a.123.1.1 (A:) automated matches {Ancestral gene}
snapslisilqaiepevvyagydntqpdttnyllsslnrlaekqlvsvvkwakalpgfrn
lhlddqmtliqyswmglmafamgwrsykhtngqmlyfapdlifneqrmqqsamydlcqgm
qqisqefvrlqvtqeeflcmkallllstvpkeglksqasfdemrmnyikelnraiakken
nsaqnwqrfyqltklldsmhdlvggllqfcfytfvqsqalsvefpemlveiisaqlpkvl
agmakpllfhk

Timeline for d4ltwa_:

• d4ltwa_ first appeared in SCOPe 2.03
  
• d4ltwa_ appears in SCOPe 2.05
  
• d4ltwa_ appears in SCOPe 2.07
  
• d4ltwa_ appears in the current release, SCOPe 2.08