Lineage for d3wi6a_ (3wi6 A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673283Protein MAP kinase activated protein kinase 2, mapkap2 [82789] (1 species)
    CaMK group; MAPKAPK subfamily; serine/threonine kinase
  7. 1673284Species Human (Homo sapiens) [TaxId:9606] [82790] (14 PDB entries)
  8. 1673325Domain d3wi6a_: 3wi6 A: [229988]
    automated match to d2pzyc_
    complexed with yrz

Details for d3wi6a_

PDB Entry: 3wi6 (more details), 2.99 Å

PDB Description: Crystal structure of MAPKAP Kinase-2 (MK2) in complex with non-selective inhibitor
PDB Compounds: (A:) MAP kinase-activated protein kinase 2

SCOPe Domain Sequences for d3wi6a_:

Sequence, based on SEQRES records: (download)

>d3wi6a_ d.144.1.7 (A:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens) [TaxId: 9606]}
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqafterease
imksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnslttpcy
tpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqye
fpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlked
ke

Sequence, based on observed residues (ATOM records): (download)

>d3wi6a_ d.144.1.7 (A:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens) [TaxId: 9606]}
fhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarrev
elhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdraftereaseimk
sigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettspyyvapevlgpe
dkscdmwslgvimyillcgyppfysispgmktrirmgqyefpnpewsevseevkmlirnl
lkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedke

SCOPe Domain Coordinates for d3wi6a_:

Click to download the PDB-style file with coordinates for d3wi6a_.
(The format of our PDB-style files is described here.)

Timeline for d3wi6a_: