Lineage for d4nksa_ (4nks A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543630Protein Fibroblast growth factor receptor 1 [56158] (1 species)
    PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2543631Species Human (Homo sapiens) [TaxId:9606] [56159] (46 PDB entries)
  8. 2543692Domain d4nksa_: 4nks A: [229979]
    automated match to d4f63a_
    complexed with 2m2

Details for d4nksa_

PDB Entry: 4nks (more details), 2.5 Å

PDB Description: Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex with pyrazolaminopyrimidine 3
PDB Compounds: (A:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d4nksa_:

Sequence, based on SEQRES records: (download)

>d4nksa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
lpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatekd
lsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgleys
ynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgl
ardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgv
pveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

Sequence, based on observed residues (ATOM records): (download)

>d4nksa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
lpedprwelprdrlvlgkplgqvvlaeainrvtkvavkmlkdatekdlsdlisememmkm
igkhkniinllgactqdgplyviveyaskgnlreylqarrppqlsskdlvscayqvargm
eylaskkcihrdlaarnvlvtednvmkiadfglidyykkttngrlpvkwmapealfdriy
thqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsnctnelymmmrdcw
havpsqrptfkqlvedldrivalts

SCOPe Domain Coordinates for d4nksa_:

Click to download the PDB-style file with coordinates for d4nksa_.
(The format of our PDB-style files is described here.)

Timeline for d4nksa_: