SCOPe 2.08: Domain d4nk9a_: 4nk9 A:

Lineage for d4nk9a_ (4nk9 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)

8. Domain d4nk9a_: 4nk9 A: [229977]
   automated match to d4f65a_
   complexed with 2k5, edo, so4

Details for d4nk9a_

PDB Entry: 4nk9, 2.57 Å

PDB Description: Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex with pyrazolaminopyrimidine 1

PDB Compounds: (A:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d4nk9a_:

Sequence, based on SEQRES records:

>d4nk9a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsn
qe

Sequence, based on observed residues (ATOM records):

>d4nk9a_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaiglddkpnrvtkvavkmlksdatekd
lsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppeqlss
kdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgidyykkttngrlpv
kwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsn
ctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d4nk9a_:

• d4nk9a_ first appeared in SCOPe 2.03
  
• d4nk9a_ appears in SCOPe 2.07