Lineage for d3zepc_ (3zep C:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984752Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2984753Protein automated matches [190417] (37 species)
    not a true protein
  7. 2984910Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)
  8. 2986413Domain d3zepc_: 3zep C: [229755]
    automated match to d4hvga_
    complexed with 1nx, gol

Details for d3zepc_

PDB Entry: 3zep (more details), 2.35 Å

PDB Description: crystal structure of jak3 kinase domain in complex with a pyrrolopyrazine-2-phenyl ether inhibitor
PDB Compounds: (C:) Tyrosine-protein kinase JAK3

SCOPe Domain Sequences for d3zepc_:

Sequence, based on SEQRES records: (download)

>d3zepc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqhsgpdqqrdfqreiq
ilkalhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarldasrlllyssqi
ckgmeylgsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvrepgqspifw
yapeslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgserdvpalsrllel
leegqrlpappacpaevhelmklcwapspqdrpsfsalgpqldmlws

Sequence, based on observed residues (ATOM records): (download)

>d3zepc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptifeerhlkyisqlgkgsvelcrydplgdntgalvavkqlqhsgpdqqrdfqreiqilk
alhsdfivkyrgvsygslrlvmeylpsgclrdflqrhrarldasrlllyssqickgmeyl
gsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvreqspifwyapeslsdn
ifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgserdvpalsrllelleegqrlpa
ppacpaevhelmklcwapspqdrpsfsalgpqldmlws

SCOPe Domain Coordinates for d3zepc_:

Click to download the PDB-style file with coordinates for d3zepc_.
(The format of our PDB-style files is described here.)

Timeline for d3zepc_: