Lineage for d4m0ea_ (4m0e A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2899459Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. 2899460Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families) (S)
    many members have left-handed crossover connection between strand 8 and additional strand 9
  5. 2899461Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
    automatically mapped to Pfam PF00135
  6. 2899462Protein Acetylcholinesterase [53476] (6 species)
  7. 2899477Species Human (Homo sapiens) [TaxId:9606] [53480] (52 PDB entries)
  8. 2899478Domain d4m0ea_: 4m0e A: [228381]
    automated match to d4ey6b_
    complexed with 1yl, edo, nag, no3

Details for d4m0ea_

PDB Entry: 4m0e (more details), 2 Å

PDB Description: structure of human acetylcholinesterase in complex with dihydrotanshinone i
PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d4m0ea_:

Sequence, based on SEQRES records: (download)

>d4m0ea_ c.69.1.1 (A:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvv
dgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagv
rvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqga
rvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanf
artgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa

Sequence, based on observed residues (ATOM records): (download)

>d4m0ea_ c.69.1.1 (A:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcppndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdfl
sdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvp
qvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyay
vfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgd
pneprdapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa

SCOPe Domain Coordinates for d4m0ea_:

Click to download the PDB-style file with coordinates for d4m0ea_.
(The format of our PDB-style files is described here.)

Timeline for d4m0ea_: