SCOPe 2.05: Domain d4bw1a_: 4bw1 A:

Lineage for d4bw1a_ (4bw1 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (258 PDB entries)

8. Domain d4bw1a_: 4bw1 A: [227833]
   automated match to d3p5oa_
   complexed with edo, s5b

Details for d4bw1a_

PDB Entry: 4bw1, 1.4 Å

PDB Description: The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4bw1a_:

Sequence; same for both SEQRES and ATOM records:

>d4bw1a_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d4bw1a_:

• d4bw1a_ first appeared in SCOPe 2.03
  
• d4bw1a_ appears in SCOPe 2.04
  
• d4bw1a_ is called d4bw1a1 in SCOPe 2.06
  
• d4bw1a_ appears in the current release, SCOPe 2.08, called d4bw1a1