Lineage for d4m49c1 (4m49 C:1-159)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2102557Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2102558Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2105555Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 2105594Protein Lactate dehydrogenase [51859] (18 species)
  7. 2105660Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (16 PDB entries)
  8. 2105667Domain d4m49c1: 4m49 C:1-159 [227781]
    Other proteins in same PDB: d4m49a2, d4m49b2, d4m49c2, d4m49d2
    automated match to d1i10a1
    complexed with 22y, epe, lac, nai, so4

Details for d4m49c1

PDB Entry: 4m49 (more details), 2.05 Å

PDB Description: Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18
PDB Compounds: (C:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4m49c1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4m49c1 c.2.1.5 (C:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d4m49c1:

Click to download the PDB-style file with coordinates for d4m49c1.
(The format of our PDB-style files is described here.)

Timeline for d4m49c1: