Lineage for d4fhba_ (4fhb A:)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2153715Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2153716Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2153717Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2153746Protein Dihydrofolate reductase, prokaryotic type [53599] (8 species)
  7. 2153757Species Escherichia coli [TaxId:562] [53600] (79 PDB entries)
  8. 2153859Domain d4fhba_: 4fhb A: [227463]
    Other proteins in same PDB: d4fhbd1, d4fhbd2
    automated match to d1ddsa_
    complexed with fol, nap

Details for d4fhba_

PDB Entry: 4fhb (more details), 2.8 Å

PDB Description: enhancing dhfr catalysis by binding of an allosteric regulator nanobody (nb179)
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d4fhba_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4fhba_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}

SCOPe Domain Coordinates for d4fhba_:

Click to download the PDB-style file with coordinates for d4fhba_.
(The format of our PDB-style files is described here.)

Timeline for d4fhba_: