SCOPe 2.08: Domain d4ej1b_: 4ej1 B:

Lineage for d4ej1b_ (4ej1 B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductase, prokaryotic type [53599] (9 species)

7. Species Escherichia coli [TaxId:562] [53600] (86 PDB entries)

8. Domain d4ej1b_: 4ej1 B: [227461]
   Other proteins in same PDB: d4ej1c1, d4ej1c2, d4ej1d1, d4ej1d2
   automated match to d1ddsa_
   complexed with fol, po4

Details for d4ej1b_

PDB Entry: 4ej1, 1.75 Å

PDB Description: Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex

PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d4ej1b_:

Sequence; same for both SEQRES and ATOM records:

>d4ej1b_ c.71.1.1 (B:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

Timeline for d4ej1b_:

• d4ej1b_ first appeared in SCOPe 2.03
  
• d4ej1b_ appears in SCOPe 2.07