SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: automated matches

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2113070Family c.37.1.14: RNA helicase [52724] (4 protein domains)
    duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension
  6. 2113149Protein automated matches [226986] (7 species)
    not a true protein

Species:

  1. 2113150Dengue virus 4 [TaxId:408688] [230921] (9 PDB entries)
    1. Domain for 2jlq:
    2. Domain for 2jlr:
    3. Domain for 2jls:
    4. Domains for 2jlu:
      1. 2113153Domain d2jlua1: 2jlu A:172-482 [230926]
        Other proteins in same PDB: d2jlua2, d2jlub2
        automated match to d2bhra2
        protein/RNA complex; complexed with gol
      2. 2113154Domain d2jlub1: 2jlu B:172-482 [230925]
        Other proteins in same PDB: d2jlua2, d2jlub2
        automated match to d2bhra2
        protein/RNA complex; complexed with gol
    5. Domains for 2jlv:
      1. 2113160Domain d2jlva1: 2jlv A:172-482 [230928]
        Other proteins in same PDB: d2jlva2, d2jlva3, d2jlvb2, d2jlvb3
        automated match to d2bhra2
        protein/RNA complex; complexed with anp, cl, gol, mn
      2. 2113161Domain d2jlvb1: 2jlv B:172-482 [230930]
        Other proteins in same PDB: d2jlva2, d2jlva3, d2jlvb2, d2jlvb3
        automated match to d2bhra2
        protein/RNA complex; complexed with anp, cl, gol, mn
    6. Domains for 2jlw:
      1. 2113164Domain d2jlwa1: 2jlw A:172-482 [230927]
        Other proteins in same PDB: d2jlwa2, d2jlwb2
        automated match to d2bhra2
        protein/RNA complex; complexed with gol, po4
      2. 2113165Domain d2jlwb1: 2jlw B:172-482 [230929]
        Other proteins in same PDB: d2jlwa2, d2jlwb2
        automated match to d2bhra2
        protein/RNA complex; complexed with gol, po4
    7. Domains for 2jlx:
      1. 2113158Domain d2jlxa1: 2jlx A:172-482 [230931]
        Other proteins in same PDB: d2jlxa2, d2jlxa3, d2jlxb2
        automated match to d2bhra2
        protein/RNA complex; complexed with adp, cl, mn, vo4
      2. 2113159Domain d2jlxb1: 2jlx B:172-482 [230932]
        Other proteins in same PDB: d2jlxa2, d2jlxa3, d2jlxb2
        automated match to d2bhra2
        protein/RNA complex; complexed with adp, cl, mn, vo4
    8. Domains for 2jly:
      1. 2113162Domain d2jlya1: 2jly A:172-482 [230934]
        Other proteins in same PDB: d2jlya2, d2jlya3, d2jlyb2, d2jlyb3
        automated match to d2bhra2
        protein/RNA complex; complexed with adp, gol, mn, po4
      2. 2113163Domain d2jlyb1: 2jly B:172-482 [230936]
        Other proteins in same PDB: d2jlya2, d2jlya3, d2jlyb2, d2jlyb3
        automated match to d2bhra2
        protein/RNA complex; complexed with adp, gol, mn, po4
    9. Domains for 2jlz:
      1. 2113156Domain d2jlza1: 2jlz A:172-482 [230933]
        Other proteins in same PDB: d2jlza2, d2jlzb2
        automated match to d2bhra2
        protein/RNA complex; complexed with adp, cl, gol, mn
      2. 2113157Domain d2jlzb1: 2jlz B:172-482 [230935]
        Other proteins in same PDB: d2jlza2, d2jlzb2
        automated match to d2bhra2
        protein/RNA complex; complexed with adp, cl, gol, mn
  2. 2113166Hepatitis c virus (isolate taiwan) [TaxId:31645] [225628] (1 PDB entry)
  3. 2113168Hepatitis C virus [TaxId:11103] [311460] (2 PDB entries)
    1. Domain for 4wxp:
    2. Domains for 4wxr:
      1. 2113170Domain d4wxra2: 4wxr A:326-627 [309922]
        Other proteins in same PDB: d4wxra1, d4wxrb1
        automated match to d4oksb2
        complexed with 3vz
      2. 2113171Domain d4wxrb2: 4wxr B:326-629 [309924]
        Other proteins in same PDB: d4wxra1, d4wxrb1
        automated match to d4oksb2
        complexed with 3vz
  4. 2113172West nile virus [TaxId:11078] [255564] (1 PDB entry)
  5. 2274109Hepatitis c virus genotype 1b (isolate con1) [TaxId:333284] [317410] (1 PDB entry)
  6. 2274507Zika virus [TaxId:64320] [317808] (8 PDB entries)
    1. Domain for 5jmt:
    2. Domain for 5jps:
    3. Domain for 5jrz:
    4. Domain for 5jwh:
    5. Domain for 5k8i:
    6. Domain for 5k8l:
    7. Domain for 5k8t:
    8. Domain for 5k8u:
  7. 2283961Zika virus (strain mr 766) [TaxId:64320] [327262] (1 PDB entry)

More info for Protein automated matches from c.37.1.14: RNA helicase

Timeline for Protein automated matches from c.37.1.14: RNA helicase: