SCOPe 2.08: Domain d4ka3a_: 4ka3 A:

Lineage for d4ka3a_ (4ka3 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase p38 [56129] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56131] (111 PDB entries)

8. Domain d4ka3a_: 4ka3 A: [224232]
   automated match to d1leza_

Details for d4ka3a_

PDB Entry: 4ka3, 2.71 Å

PDB Description: Structure of MAP kinase in complex with a docking peptide

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d4ka3a_:

Sequence, based on SEQRES records:

>d4ka3a_ d.144.1.7 (A:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld

Sequence, based on observed residues (ATOM records):

>d4ka3a_ d.144.1.7 (A:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglaatrwyrapeim
lnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkisses
arnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdp
ddepvadpydqsfesrdllidewksltydevisfvpppld

Timeline for d4ka3a_:

• d4ka3a_ first appeared in SCOPe 2.03
  
• d4ka3a_ appears in SCOPe 2.07