Lineage for d4jnka1 (4jnk A:1-159)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1346342Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 1346343Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 1348919Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 1348958Protein Lactate dehydrogenase [51859] (17 species)
  7. 1349005Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (3 PDB entries)
  8. 1349006Domain d4jnka1: 4jnk A:1-159 [223911]
    Other proteins in same PDB: d4jnka2, d4jnkb2, d4jnkc2, d4jnkd2
    automated match to d1i10a1
    complexed with epe, lac, nai, so4, zhk

Details for d4jnka1

PDB Entry: 4jnk (more details), 1.9 Å

PDB Description: Lactate Dehydrogenase A in complex with inhibitor compound 22
PDB Compounds: (A:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4jnka1:

Sequence, based on SEQRES records: (download)

>d4jnka1 c.2.1.5 (A:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvig

Sequence, based on observed residues (ATOM records): (download)

>d4jnka1 c.2.1.5 (A:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarsrlnlvqrnvnifkfiipnvvk
yspnckllivsnpvdiltyvawkisgfpknrvig

SCOPe Domain Coordinates for d4jnka1:

Click to download the PDB-style file with coordinates for d4jnka1.
(The format of our PDB-style files is described here.)

Timeline for d4jnka1: