Lineage for d4j99b_ (4j99 B:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1433619Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1435613Protein automated matches [190091] (11 species)
    not a true protein
  7. 1435681Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)
  8. 1435750Domain d4j99b_: 4j99 B: [223633]
    automated match to d3ky2a_
    complexed with acp, mg, so4; mutant

Details for d4j99b_

PDB Entry: 4j99 (more details), 1.85 Å

PDB Description: crystal structure of fgf receptor 2 (fgfr2) kinase domain harboring the gain-of-function k659t mutation.
PDB Compounds: (B:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d4j99b_:

Sequence, based on SEQRES records: (download)

>d4j99b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgmey
sydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfg
lardinnidyyktttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypg
ipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

Sequence, based on observed residues (ATOM records): (download)

>d4j99b_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgmey
sydqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinn
idyyktttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelf
kllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

SCOPe Domain Coordinates for d4j99b_:

Click to download the PDB-style file with coordinates for d4j99b_.
(The format of our PDB-style files is described here.)

Timeline for d4j99b_: