SCOPe 2.08: Domain d4ih6a1: 4ih6 A:2-562

Lineage for d4ih6a1 (4ih6 A:2-562)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein Viral RNA polymerase [56695] (17 species)

7. Species Hepatitis C virus [TaxId:11103] [56697] (72 PDB entries)

8. Domain d4ih6a1: 4ih6 A:2-562 [223172]
   Other proteins in same PDB: d4ih6a2, d4ih6b2
   automated match to d3mf5a_
   complexed with 1ep

Details for d4ih6a1

PDB Entry: 4ih6, 2.2 Å

PDB Description: Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds

PDB Compounds: (A:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d4ih6a1:

Sequence, based on SEQRES records:

>d4ih6a1 e.8.1.4 (A:2-562) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
msytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihs
vwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvst
lpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyq
ccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasa
acraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydle
litscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwa
rmilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspge
inrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipa
asrldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d4ih6a1 e.8.1.4 (A:2-562) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
msytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvld
dhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihs
vwkdlledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqvv
mgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdla
pearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacraa
klqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydlelitsc
ssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilm
thffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrva
sclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipaasrld
lsgwfvagysggdiyh

Timeline for d4ih6a1:

• d4ih6a1 first appeared in SCOPe 2.03, called d4ih6a_
  
• d4ih6a1 appears in SCOPe 2.07