SCOPe 2.05: Domain d4iclb_: 4icl B:

Lineage for d4iclb_ (4icl B:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein automated matches [190211] (5 species)
   not a true protein

7. Species Human immunodeficiency virus type 1 [TaxId:11678] [226272] (12 PDB entries)

8. Domain d4iclb_: 4icl B: [223124]
   Other proteins in same PDB: d4icla2
   automated match to d1hqeb_
   protein/DNA complex; protein/RNA complex; complexed with 14n, dms, mg, t27

Details for d4iclb_

PDB Entry: 4icl, 1.8 Å

PDB Description: hiv-1 reverse transcriptase with bound fragment at the incoming dntp binding site

PDB Compounds: (B:) p51 RT

SCOPe Domain Sequences for d4iclb_:

Sequence, based on SEQRES records:

>d4iclb_ e.8.1.2 (B:) automated matches {Human immunodeficiency virus type 1 [TaxId: 11678]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyq

Sequence, based on observed residues (ATOM records):

>d4iclb_ e.8.1.2 (B:) automated matches {Human immunodeficiency virus type 1 [TaxId: 11678]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglflwmgyelhpdkwtvqpivlpekdswtvnd
iqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhg
vyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkit
tesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

Timeline for d4iclb_:

• d4iclb_ first appeared in SCOPe 2.03
  
• d4iclb_ appears in SCOPe 2.04
  
• d4iclb_ appears in SCOPe 2.06
  
• d4iclb_ appears in the current release, SCOPe 2.08