SCOPe 2.05: Domain d4hxpa_: 4hxp A:

Lineage for d4hxpa_ (4hxp A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (258 PDB entries)

8. Domain d4hxpa_: 4hxp A: [222778]
   automated match to d3uvya_
   complexed with 1a5

Details for d4hxpa_

PDB Entry: 4hxp, 1.73 Å

PDB Description: brd4 bromodomain 1 complex with 4-(2-oxo-1,3-oxazolidin-3-yl)benzamide inhibitor

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4hxpa_:

Sequence; same for both SEQRES and ATOM records:

>d4hxpa_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
elpt

Timeline for d4hxpa_:

• d4hxpa_ first appeared in SCOPe 2.03
  
• d4hxpa_ appears in SCOPe 2.04
  
• d4hxpa_ is called d4hxpa1 in SCOPe 2.06
  
• d4hxpa_ appears in the current release, SCOPe 2.08, called d4hxpa1