Lineage for d4hxma1 (4hxm A:44-166)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2319937Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  4. 2319938Superfamily a.29.2: Bromodomain [47370] (2 families) (S)
  5. 2320170Family a.29.2.0: automated matches [191428] (1 protein)
    not a true family
  6. 2320171Protein automated matches [190615] (14 species)
    not a true protein
  7. 2320183Species Human (Homo sapiens) [TaxId:9606] [187641] (1004 PDB entries)
  8. 2320294Domain d4hxma1: 4hxm A:44-166 [222775]
    Other proteins in same PDB: d4hxma2
    automated match to d3uvya_
    complexed with 1a8

Details for d4hxma1

PDB Entry: 4hxm (more details), 1.5 Å

PDB Description: brd4 bromodomain 1 complex with n-{3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)-5-[(thiophen-2-ylsulfonyl)amino]phenyl}butanamide inhibitor
PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4hxma1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4hxma1 a.29.2.0 (A:44-166) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lpt

SCOPe Domain Coordinates for d4hxma1:

Click to download the PDB-style file with coordinates for d4hxma1.
(The format of our PDB-style files is described here.)

Timeline for d4hxma1:

View in 3D
Domains from same chain:
(mouse over for more information)
d4hxma2