Lineage for d4hxla1 (4hxl A:44-167)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1993780Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  4. 1993781Superfamily a.29.2: Bromodomain [47370] (2 families) (S)
  5. 1993941Family a.29.2.0: automated matches [191428] (1 protein)
    not a true family
  6. 1993942Protein automated matches [190615] (10 species)
    not a true protein
  7. 1993960Species Human (Homo sapiens) [TaxId:9606] [187641] (647 PDB entries)
  8. 1993992Domain d4hxla1: 4hxl A:44-167 [222774]
    Other proteins in same PDB: d4hxla2
    automated match to d2nxba_
    complexed with 1a9

Details for d4hxla1

PDB Entry: 4hxl (more details), 1.52 Å

PDB Description: brd4 bromodomain 1 complex with 3-cyclohexyl-n-{3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)-5-[(thiophen-2-ylsulfonyl)amino]phenyl}propanamide inhibitor
PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4hxla1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4hxla1 a.29.2.0 (A:44-167) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lpte

SCOPe Domain Coordinates for d4hxla1:

Click to download the PDB-style file with coordinates for d4hxla1.
(The format of our PDB-style files is described here.)

Timeline for d4hxla1:

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Domains from same chain:
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d4hxla2