SCOPe 2.03: Domain d4hnfa_: 4hnf A:

Lineage for d4hnfa_ (4hnf A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Casein kinase-1, CK1 [56139] (4 species)
   OPK group; CKI subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [224941] (6 PDB entries)

8. Domain d4hnfa_: 4hnf A: [222685]
   automated match to d3uzpa_
   complexed with 16w

Details for d4hnfa_

PDB Entry: 4hnf, 2.07 Å

PDB Description: crystal structure of ck1d in complex with pf4800567

PDB Compounds: (A:) Casein kinase I isoform delta

SCOPe Domain Sequences for d4hnfa_:

Sequence, based on SEQRES records:

>d4hnfa_ d.144.1.7 (A:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
lrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqgg
vgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsk
nfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasi
nthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlck
gypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

Sequence, based on observed residues (ATOM records):

>d4hnfa_ d.144.1.7 (A:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
lrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvkpqlhieskiykmmqggvgi
ptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsknfi
hrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasinth
lgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlckgyp
sefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnmlk

Timeline for d4hnfa_:

• d4hnfa_ is new in SCOPe 2.03-stable
  
• d4hnfa_ appears in SCOPe 2.04
  
• d4hnfa_ appears in the current release, SCOPe 2.08