SCOPe 2.05: Domain d4hhzb2: 4hhz B:136-350

Lineage for d4hhzb2 (4hhz B:136-350)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.166: ADP-ribosylation [56398] (1 superfamily)
   unusual fold

4. Superfamily d.166.1: ADP-ribosylation [56399] (8 families)

5. Family d.166.1.0: automated matches [191650] (1 protein)
   not a true family

6. Protein automated matches [191197] (7 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225406] (26 PDB entries)

8. Domain d4hhzb2: 4hhz B:136-350 [222613]
   Other proteins in same PDB: d4hhza1, d4hhzb1, d4hhzc1, d4hhzd1
   automated match to d1gs0a2
   complexed with 15s, so4

Details for d4hhzb2

PDB Entry: 4hhz, 2.72 Å

PDB Description: Crystal structure of PARP catalytic domain in complex with novel inhibitors

PDB Compounds: (B:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d4hhzb2:

Sequence; same for both SEQRES and ATOM records:

>d4hhzb2 d.166.1.0 (B:136-350) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lktdikvvdrdseeaeiirkyvknthatthnaydlevidifkieregecqrykpfkqlhn
rrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmvsksanychtsqgdpi
glillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsanisldgvdvplgtgis
sgvndtsllyneyivydiaqvnlkyllklkfnfkt

Timeline for d4hhzb2:

• d4hhzb2 first appeared in SCOPe 2.03
  
• d4hhzb2 appears in SCOPe 2.04
  
• d4hhzb2 appears in SCOPe 2.06
  
• d4hhzb2 appears in the current release, SCOPe 2.08