SCOPe 2.03: Domain d4fv6a_: 4fv6 A:

Lineage for d4fv6a_ (4fv6 A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d4fv6a_: 4fv6 A: [221551]
   automated match to d3sa0a_
   complexed with e57, edo, so4

Details for d4fv6a_

PDB Entry: 4fv6, 2.5 Å

PDB Description: Crystal Structure of the ERK2 complexed with E57

PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d4fv6a_:

Sequence, based on SEQRES records:

>d4fv6a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyv
atrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsps
qedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqal
ahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpg

Sequence, based on observed residues (ATOM records):

>d4fv6a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvaatrwyrapeimlny
tksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnyll
slphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdepia
eapfkfdmelddlpkeklkelifeetarfqpg

Timeline for d4fv6a_:

• d4fv6a_ is new in SCOPe 2.03-stable
  
• d4fv6a_ appears in SCOPe 2.04
  
• d4fv6a_ appears in the current release, SCOPe 2.08