SCOPe 2.05: Domain d4e41a1: 4e41 A:3-81

Lineage for d4e41a1 (4e41 A:3-81)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (2 families)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

6. Protein Class II MHC alpha chain, N-terminal domain [88806] (15 species)

7. Species Human (Homo sapiens), HLA-DR2 [TaxId:9606] [88809] (13 PDB entries)

8. Domain d4e41a1: 4e41 A:3-81 [220248]
   Other proteins in same PDB: d4e41a2, d4e41b1, d4e41b2, d4e41d1, d4e41d2, d4e41e1, d4e41e2, d4e41f2, d4e41g1, d4e41g2, d4e41i1, d4e41i2, d4e41j1, d4e41j2
   automated match to d1jwua2
   complexed with na; mutant

Details for d4e41a1

PDB Entry: 4e41, 2.6 Å

PDB Description: Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4

PDB Compounds: (A:) hla class II histocompatibility antigen, dr alpha chain

SCOPe Domain Sequences for d4e41a1:

Sequence; same for both SEQRES and ATOM records:

>d4e41a1 d.19.1.1 (A:3-81) Class II MHC alpha chain, N-terminal domain {Human (Homo sapiens), HLA-DR2 [TaxId: 9606]}
eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
iavdkanleimtkrsnytp

Timeline for d4e41a1:

• d4e41a1 first appeared in SCOPe 2.03
  
• d4e41a1 appears in SCOPe 2.04
  
• d4e41a1 appears in SCOPe 2.06
  
• d4e41a1 appears in the current release, SCOPe 2.08