Lineage for d4dsua_ (4dsu A:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1845072Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 1845073Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families) (S)
    division into families based on beta-sheet topologies
  5. 1845934Family c.37.1.8: G proteins [52592] (79 proteins)
    core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest
  6. 1846955Protein automated matches [190047] (27 species)
    not a true protein
  7. 1847028Species Human (Homo sapiens) [TaxId:9606] [186768] (145 PDB entries)
  8. 1847068Domain d4dsua_: 4dsu A: [220001]
    automated match to d3gftb_
    complexed with bzi, gdp, mg

Details for d4dsua_

PDB Entry: 4dsu (more details), 1.7 Å

PDB Description: Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
PDB Compounds: (A:) GTPase KRas, isoform 2B

SCOPe Domain Sequences for d4dsua_:

Sequence, based on SEQRES records: (download)

>d4dsua_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
steyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhkekmskdgkkkkkk

Sequence, based on observed residues (ATOM records): (download)

>d4dsua_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
steyklvvvgadgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qsamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsr
tvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhkekmskdgkkkkkk

SCOPe Domain Coordinates for d4dsua_:

Click to download the PDB-style file with coordinates for d4dsua_.
(The format of our PDB-style files is described here.)

Timeline for d4dsua_: