SCOPe 2.05: Domain d4dkia3: 4dki A:328-668

Lineage for d4dkia3 (4dki A:328-668)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)

6. Protein Penicillin binding protein 2a (PBP2A), C-terminal domain [82838] (1 species)

7. Species Staphylococcus aureus [TaxId:1280] [82839] (6 PDB entries)
   Uniprot O54286 27-668

8. Domain d4dkia3: 4dki A:328-668 [219829]
   Other proteins in same PDB: d4dkia1, d4dkia2, d4dkib1, d4dkib2
   automated match to d1vqqa3
   complexed with bct, cd, cl, rb6

Details for d4dkia3

PDB Entry: 4dki, 2.9 Å

PDB Description: Structural Insights into the Anti- Methicillin-Resistant Staphylococcus aureus (MRSA) Activity of Ceftobiprole

PDB Compounds: (A:) Penicillin-binding protein 2'

SCOPe Domain Sequences for d4dkia3:

Sequence, based on SEQRES records:

>d4dkia3 e.3.1.1 (A:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
idakvqksiynnmkndygsgtaihpqtgellalvstpsydvypfmygmsneeynkltedk
kepllnkfqittspgstqkiltamiglnnktlddktsykidgkgwqkdkswggynvtrye
vvngnidlkqaiessdniffarvalelgskkfekgmkklgvgedipsdypfynaqisnkn
ldneilladsgygqgeilinpvqilsiysalenngninaphllkdtknkvwkkniisken
inlltdgmqqvvnkthkediyrsyanligksgtaelkmkqgetgrqigwfisydkdnpnm
mmainvkdvqdkgmasynakisgkvydelyengnkkydide

Sequence, based on observed residues (ATOM records):

>d4dkia3 e.3.1.1 (A:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
idakvqksiynnmkndygsgtaihpqtgellalvstpsydvypfmygmsneeynkltedk
kepllnkfqittspgstqkiltamiglnnktlddktsykidgkgwqkdkswggynvtrye
vvngnidlkqaiessdniffarvalelgskkfekgmkklgvgedipsdypfynaqisnkn
ldneilladsgygqgeilinpvqilsiysalenngninaphllkdtknkvwkkniisken
inlltdgmqqvvnkthkediyrsyanligksgtaelkmkqetgrqigwfisydkdnpnmm
mainvkdvqdmasynakisgkvydelyengnkkydide

Timeline for d4dkia3:

• d4dkia3 first appeared in SCOPe 2.03
  
• d4dkia3 appears in SCOPe 2.04
  
• d4dkia3 appears in SCOPe 2.06
  
• d4dkia3 appears in the current release, SCOPe 2.08