SCOPe 2.04: Domain d4dgga_: 4dgg A:

Lineage for d4dgga_ (4dgg A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (2 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (35 PDB entries)

8. Domain d4dgga_: 4dgg A: [219751]
   automated match to d2gqgb_
   complexed with i76

Details for d4dgga_

PDB Entry: 4dgg, 2.65 Å

PDB Description: c-SRC kinase domain in complex with RM-1-176

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d4dgga_:

Sequence, based on SEQRES records:

>d4dgga_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
akdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmk
klrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgma
yvermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaal
ygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlm
cqcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d4dgga_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
akdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmk
klrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgma
yvermnyvhrdlraanilvgenlvckvadfgfpikwtapeaalygrftiksdvwsfgill
telttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeyl
qafledyftstepqyqpgenl

Timeline for d4dgga_:

• d4dgga_ first appeared in SCOPe 2.03
  
• d4dgga_ appears in SCOPe 2.05
  
• d4dgga_ appears in the current release, SCOPe 2.08