SCOPe 2.06: Domain d4b8mb_: 4b8m B:

Lineage for d4b8mb_ (4b8m B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species African clawed frog (Xenopus laevis) [TaxId:8355] [187456] (11 PDB entries)

8. Domain d4b8mb_: 4b8m B: [219366]
   automated match to d2bfyb_
   complexed with vx6

Details for d4b8mb_

PDB Entry: 4b8m, 1.85 Å

PDB Description: Aurora B kinase in complex with VX-680

PDB Compounds: (B:) aurora kinase b-a

SCOPe Domain Sequences for d4b8mb_:

Sequence; same for both SEQRES and ATOM records:

>d4b8mb_ d.144.1.7 (B:) automated matches {African clawed frog (Xenopus laevis) [TaxId: 8355]}
talaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehq
lrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfm
eeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylp
pemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgsk
dliskllryhppqrlplkgvmehpwvkansrrvlppvyqs

Timeline for d4b8mb_:

• d4b8mb_ first appeared in SCOPe 2.03
  
• d4b8mb_ appears in SCOPe 2.05
  
• d4b8mb_ appears in SCOPe 2.07
  
• d4b8mb_ appears in the current release, SCOPe 2.08