SCOPe 2.08: Domain d4at4a1: 4at4 A:543-838

Lineage for d4at4a1 (4at4 A:543-838)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4at4a1: 4at4 A:543-838 [219131]
   Other proteins in same PDB: d4at4a2
   automated match to d3gqia_
   complexed with t6e

Details for d4at4a1

PDB Entry: 4at4, 2.36 Å

PDB Description: crystal structure of trkb kinase domain in complex with ex429

PDB Compounds: (A:) bdnf/nt-3 growth factors receptor

SCOPe Domain Sequences for d4at4a1:

Sequence, based on SEQRES records:

>d4at4a1 d.144.1.0 (A:543-838) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dtfvqhikrhnivlkrelgegafgkvflaecynlcpeqdkilvavktlkdasdnarkdfh
reaelltnlqhehivkfygvcvegdplimvfeymkhgdlnkflrahgpdavlmaegnppt
eltqsqmlhiaqqiaagmvylasqhfvhrdlatrnclvgenllvkigdfgmsrdvystdy
yrvgghtmlpirwmppesimyrkfttesdvwslgvvlweiftygkqpwyqlsnnevieci
tqgrvlqrprtcpqevyelmlgcwqrephmrknikgihtllqnlakaspvyldilg

Sequence, based on observed residues (ATOM records):

>d4at4a1 d.144.1.0 (A:543-838) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dtfvqhikrhnivlkrelgegafgkvflaecynlckilvavktlkdasdnarkdfhreae
lltnlqhehivkfygvcvegdplimvfeymkhgdlnkflrahgpdavlmappteltqsqm
lhiaqqiaagmvylasqhfvhrdlatrnclvgenllvkigdfgmsrdvystdyyrvgght
mlpirwmppesimyrkfttesdvwslgvvlweiftygkqpwyqlsnneviecitqgrvlq
rprtcpqevyelmlgcwqrephmrknikgihtllqnlakaspvyldilg

Timeline for d4at4a1:

• d4at4a1 first appeared in SCOPe 2.03, called d4at4a_
  
• d4at4a1 appears in SCOPe 2.07