Lineage for d4agwa_ (4agw A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984752Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2984753Protein automated matches [190417] (37 species)
    not a true protein
  7. 2984864Species Chicken (Gallus gallus) [TaxId:9031] [225619] (9 PDB entries)
  8. 2984881Domain d4agwa_: 4agw A: [218856]
    automated match to d2gqgb_
    complexed with gol, mes, ng7; mutant

Details for d4agwa_

PDB Entry: 4agw (more details), 2.6 Å

PDB Description: discovery of a small molecule type ii inhibitor of wild-type and gatekeeper mutants of bcr-abl, pdgfralpha, kit, and src kinases
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d4agwa_:

Sequence, based on SEQRES records: (download)

>d4agwa_ d.144.1.0 (A:) automated matches {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
lrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaaly
grftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmc
qcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records): (download)

>d4agwa_ d.144.1.0 (A:) automated matches {Chicken (Gallus gallus) [TaxId: 9031]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
lrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfpikwtapeaalygrftiksdvwsfgilltel
ttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqaf
ledyftstepqyqpgenl

SCOPe Domain Coordinates for d4agwa_:

Click to download the PDB-style file with coordinates for d4agwa_.
(The format of our PDB-style files is described here.)

Timeline for d4agwa_: